ConclusionĬompound III-17 had a good potential for further development as a new bactericide for controlling Xoc. Moreover, this compound also demonstrated good protection and curative activities in vivo against rice bacterial leaf streak caused by Xoc. Work the way you want Apply for jobs, create easy-to-by projects, or access exclusive opportunities that come to you. Further measurements of EC 50 values showed that compound III-17 bearing a 4-methoxyphenyl group had the best anti- Xoc efficacy (EC 50 = 12.4 μg/mL), far better than the commercialized Bismerthiazol (77.5 μg/mL). Adobe Photoshop Image Editing Photo Manipulation How it works Create your free profile Highlight your skills and experience, show your portfolio, and set your ideal pay rate. The bioassay results indicated that some compounds displayed noticeable inhibitory effects in vitro against Xanthomonas oryzae pv. ResultsĪll of the target compounds were fully characterized by 1H NMR, 13C NMR, and high-resolution mass spectra, and compound III-6 containing a 3-bromophenyl substituent was clearly confirmed via single-crystal X-ray diffraction analysis. To discover more efficient antimicrobial agents in agriculture, a series of new quinazoline derivatives bearing both sulfonate ester and piperidine-4-carboxamide moieties were synthesized and assessed for their antimicrobial effects.
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